Fig. 10. Summary figure of polarized radiographs focused on the spine from one cohort (CC1) of experimental animals. (A) Paired female CC1-633; (B) paired male CC1-893; (C) colony control CC1-3581. In each panel, the first radiograph was taken during the baseline period; the second radiograph was taken at the end of the study (45 weeks after removal from reproductive suppression). The horizontal line in the center of each radiograph is aligned with the top of the vertebral body of L1. The diagram illustrates contrasts in lumbar lengthening from the beginning to the end of the study across experimental groups. The number on the center of the horizontal line indicates the percent of length gained in the lumbar spine by that animal over the duration of the 50-week study. The radiopaque cylindrical objects seen near the cervical spine are identification microchip implants.