Fig. 5. Duty cycle and filament stiffness influence how work and ATP vary with
respect to phase of activation (
Ca). Similar to
Fig. 4, lines represent mean
work (A), ATP (B) and efficiency (C) values; however error bars are not shown.
Duty faction (
Ca) varied between 0.1 (blue), 0.2 (green) and
0.5 (black). Broken lines represent our standard mechanical parameters for the
filaments and cross-bridges, listed in Fig.
2. Therefore, the mean data shown in
Fig. 4 correspond to the grey
broken lines shown here in Fig. 5. Solid lines represent a more compliant
filament lattice, where both ka and km
were simultaneous scaled by a factor of 0.1 (kxb did not
change). As in Fig. 4, note the
difference in ordinate scale between the left and right panels in A and C when
=0.05 (left) versus 0.025 (right).