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Journal of Experimental Biology 11,273-278 (1934)
Published by Company of Biologists 1934

Retardation of Growth in Axolotls Resulting from Parathyroid Extract Administration

J. H. THOMPSON ¹ and JULIAN S. HUXLEY ¹

¹ Physiological and Zoological Laboratories, King's College, University of London, and the Royal College of Surgeons, London

Axolotls have been used in a series of experiments designed to test the growth-retarding properties of the parathyroid glands of mammals, prepared so as to include the anti-growth hormone. Such retardation of growth has been obtained, and is proportional to dosage. This extends the growth-retarding effect of this hormone to the Anamnia, and to forms which presumably have no parathyroid themselves.

A lightening of colour in normally dark pigmented individuals was noted after a considerable period (about eight weeks) of treatment.