|
| |
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Journal of Experimental Biology, Vol 203, Issue 5 927-933, Copyright © 2000 by Company of Biologists
JOURNAL ARTICLES |
JF Kaluza and H Breer
University of Stuttgart-Hohenheim, Institute of Physiology, Germany.
The responsiveness of isolated olfactory sensory neurons to stimulation with aliphatic aldehydes of varying chain length (5-10 hydrogenated carbon atoms) was investigated by means of Ca(2+ )imaging. More than half the cells examined were responsive to aliphatic aldehydes. Individual cells did not react or reacted to one or multiple aldehydes; in the latter case, cells only reacted to aldehydes of consecutive carbon chain lengths. The largest proportion of cells responded to octanal. It was also demonstrated that a structural difference as small as one hydrogenated carbon atom was detectable by the olfactory neurons. Neurons were increasingly able to discriminate between two aldehydes as the difference in chain length between the two increased. Discrimination between aldehydes with longer carbon chains was reduced. Although the odorants examined belong to a distinct chemical class and differ only slightly in structure, individual olfactory sensory neurons showed quite different receptive properties.
This article has been cited by other articles:
|
|
 |
|
  M. Laska Olfactory Discrimination Ability for Aliphatic C6 Alcohols as a Function of Presence, Position, and Configuration of a Double Bond Chem Senses, November 1, 2005; 30(9): 755 - 760. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Sanz, C. Schlegel, J.-C. Pernollet, and L. Briand Comparison of Odorant Specificity of Two Human Olfactory Receptors from Different Phylogenetic Classes and Evidence for Antagonism Chem Senses, January 1, 2005; 30(1): 69 - 80. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Bieri, K. Monastyrskaia, and B. Schilling Olfactory Receptor Neuron Profiling using Sandalwood Odorants Chem Senses, July 1, 2004; 29(6): 483 - 487. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. C. Araneda, Z. Peterlin, X. Zhang, A. Chesler, and S. Firestein A pharmacological profile of the aldehyde receptor repertoire in rat olfactory epithelium J. Physiol., March 15, 2004; 555(3): 743 - 756. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Laska, A. Wieser, R. M. Rivas Bautista, and L. T. Hernandez Salazar Olfactory Sensitivity for Carboxylic Acids in Spider Monkeys and Pigtail Macaques Chem Senses, February 1, 2004; 29(2): 101 - 109. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Hamana, J. Hirono, M. Kizumi, and T. Sato Sensitivity-dependent Hierarchical Receptor Codes for Odors Chem Senses, February 1, 2003; 28(2): 87 - 104. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. A. Wilson Receptive Fields in the Rat Piriform Cortex Chem Senses, June 1, 2001; 26(5): 577 - 584. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. A. Wilson Comparison of Odor Receptive Field Plasticity in the Rat Olfactory Bulb and Anterior Piriform Cortex J Neurophysiol, December 1, 2000; 84(6): 3036 - 3042. [Abstract] [Full Text] [PDF]
|
|
