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Figure 4


Fig. 4. X-organ neuron sensitivity to HA. (A) Representative HA-evoked currents obtained at –40 mV holding potential, during application of HA pulses at the indicated concentrations. (B) Peak currents (mean ± s.e.m.) versus HA concentration (3–5 observations per point). The solid line correspond to a non-linear regression using Imax=1/[1+(EC50/HA)n], where HA=molar HA concentration, n=the Hill coefficient and EC50=HA concentration giving half-maximal effect, being the free parameters. The fit yielded EC50=3.3±1 µmol l–1 and n=2.6±0.4.





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